Pazopanib in advanced desmoplastic small round cell tumours: a multi-institutional experience
نویسندگان
چکیده
منابع مشابه
A 8-year survivor of unresectable intrapelvic desmoplastic small round cell tumor treated with concurrent chemoradiotherapy
Desmoplastic small round cell tumor is a rare malignant tumor that occurs primarily in young males. Here, a case of small round cell tumor in an adult male successfully treated with a curative concurrent chemoradiotherapy is presented. A 58-year-old man had an intrapelvic tumor. Surgical resection was attempted, but the tumor was unresectable. Needle biopsy was performed and the diagno...
متن کاملIntra-abdominal desmoplastic small round cell tumor
BACKGROUND The desmoplastic small round cell tumour is a rare and aggressive intra-abdominal neoplasia, with only 200 cases reported, and a higher incidence in men and predilection for the second decade of life. Histologically characterized by the presence of small nests of undifferentiated tumour cells, wrapped in fibrous desmoplastic stroma. CLINICAL CASE A 24 year old male started with abd...
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Desmoplastic small round cell tumor (DSRCT) is an extremely uncommon, highly aggressive, and malignant mesenchymal neoplasm of undetermined histogenesis. Less than 200 case reports have been documented in literature so far. Herein, we report a 26-year-old otherwise healthy female patient who presented with a 1-month history of epigastric pain. On physical examination, a palpable, slightly mobil...
متن کاملDesmoplastic small-round-cell rectal tumor
A 22-year-old male presented with abdominal and back pain and significant weight loss. On examination he was cachectic with a large palpable mass arising from the pelvis. A digital rectal exam revealed an obstructed rectal mass 5 cms from the anal verge. A contrast-enhanced computed tomography (CT) scan of the abdomen revealed a rectal mass with peritoneal metastasis in the form of extensive pe...
متن کاملDesmoplastic Small Round Cell Tumor (DSRCT)
Desmoplastic small round cell tumor (DSRCT) is an aggressive malignant neoplasm that occurs in adolescents and young adults. This tumor can co-express epithelial, neuronal, and mesenchymal markers. Clinical manifestations are often related to widespread abdominal disease. Distant metastases can be present at the time of diagnosis. The molecular hallmark of DSCRT is the EWS-WT1 fusion protein. T...
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ژورنال
عنوان ژورنال: Clinical Sarcoma Research
سال: 2014
ISSN: 2045-3329
DOI: 10.1186/2045-3329-4-7